BDBM26400 2,4-diamino-5,6-disubstituted pyrimidine, 14::9-phenyl-4-(piperazin-1-yl)-5H,6H,7H,8H,9H-cyclohepta[d]pyrimidin-2-amine
SMILES Nc1nc2C(CCCCc2c(n1)N1CCNCC1)c1ccccc1
InChI Key InChIKey=LTSQOGQDXSXTPV-UHFFFAOYSA-N
Data 6 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 26400
Affinity DataKi: 4.47nMAssay Description:Displacement of [3H]-histamine from rat histamine H4 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 4.5nM ΔG°: -11.4kcal/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Affinity DataKi: 39.8nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 40nM ΔG°: -10.1kcal/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Affinity DataKi: 661nMAssay Description:Displacement of [3H]NAMH from rat histamine H3 receptor expressed in C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.24E+3nMAssay Description:Displacement of [3H]NAMH from human histamine H3 receptor expressed in C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair