BDBM26579 3-({[4-(carboxymethyl)phenyl]methyl}sulfanyl)-8-methyl-5H-[1,2,4]triazino[5,6-b]indole-5-carboxylic acid::H1-A1NI2, 4

SMILES Cc1ccc2n(C(O)=O)c3nc(SCc4ccc(CC(O)=O)cc4)nnc3c2c1

InChI Key InChIKey=QVMJVFSHVPPKCP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26579   

TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
University of Southern California

LigandPNGBDBM26579(3-({[4-(carboxymethyl)phenyl]methyl}sulfanyl)-8-me...)
Affinity DataIC50:  1.50E+4nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed