BDBM26588 2-[10-(carboxymethyl)-6,12-dioxo-5,11-dioxatricyclo[7.3.0.0^{3,7}]dodeca-1,3(7),8-trien-4-yl]acetic acid::H1-A1NI2, 13

SMILES OC(=O)CC1OC(=O)c2cc3C(CC(O)=O)OC(=O)c3cc12

InChI Key InChIKey=IUKYJNCDSUILBM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26588   

TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
University of Southern California

LigandPNGBDBM26588(2-[10-(carboxymethyl)-6,12-dioxo-5,11-dioxatricycl...)
Affinity DataIC50:  1.10E+4nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed