BDBM26594 2-(5-{[2-(2-carboxyphenyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl]carbonyl}-1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)benzoic acid::A1NI2-A3NI1,19

SMILES OC(=O)c1ccccc1N1C(=O)c2ccc(cc2C1=O)C(=O)c1ccc2C(=O)N(C(=O)c2c1)c1ccccc1C(O)=O

InChI Key InChIKey=KQBXFXSFTTUBLR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26594   

TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
University of Southern California

LigandPNGBDBM26594(2-(5-{[2-(2-carboxyphenyl)-1,3-dioxo-2,3-dihydro-1...)
Affinity DataIC50:  8.00E+3nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed