BDBM26604 2-{3-[(5Z)-3-(4-bromophenyl)-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]-2-oxo-2,3-dihydro-1H-indol-1-yl}acetic acid::oxoindole-thioxothiazolidinone, 29

SMILES OC(=O)CN1C(=O)\C(=C2/SC(=S)N(C2=O)c2ccc(Br)cc2)c2ccccc12

InChI Key InChIKey=FECOXZWWSSYGKH-NXVVXOECSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26604   

TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
University of Southern California

LigandPNGBDBM26604(2-{3-[(5Z)-3-(4-bromophenyl)-4-oxo-2-sulfanylidene...)
Affinity DataIC50:  6.00E+3nMAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed