BDBM267990 4-[2-(morpholin-4-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-4-yl]pyridin-2(1H)-one::US10772893, Example 351::US11529356, Example 351::US9549932, 22::US9549932, 351

SMILES COc1cc(ccn1)-c1cc(nc2c(nccc12)-c1ccn[nH]1)N1CCOCC1

InChI Key InChIKey=WRVNLAIBRYKYSB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 267990   

TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM267990(4-[2-(morpholin-4-yl)-8-(1H-pyrazol-5-yl)-1,7-naph...)
Affinity DataIC50:  465nMpH: 7.0Assay Description:To determine of binding activity of the test compounds, full-length human ATR protein was expressed and purified together with ATRIP as described abo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM267990(4-[2-(morpholin-4-yl)-8-(1H-pyrazol-5-yl)-1,7-naph...)
Affinity DataIC50:  154nMpH: 7.0Assay Description:To determine of binding activity of the test compounds, full-length human ATR protein was expressed and purified together with ATRIP as described abo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent