BDBM269262 US10071086, Compound 10

SMILES CN1CCN(Cc2cc(F)cc(c2)-c2cncc3[nH]c(nc23)-c2n[nH]c3ncc(cc23)-c2cccnc2)CC1

InChI Key InChIKey=ULWIWKNRZYQIBH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 269262   

TargetBeta-catenin-interacting protein 1(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM269262(US10071086, Compound 10)
Affinity DataIC50:  247nMAssay Description:Compounds of Formulas (I) or (II) were screened in a β-catenin-based reporter assay in a transformed human bronchial epithelial cell line (NL-20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM269262(US10071086, Compound 10)
Affinity DataIC50:  263nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent