BDBM26979 CHEMBL69710::Cl-::POTASSIUM CHLORIDE::SODIUM CHLORIDE::chloride::chloride ion

SMILES [Cl-]

InChI Key InChIKey=VEXZGXHMUGYJMC-UHFFFAOYSA-M

Data  52 KI  1 EC50

PDB links: 17862 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 26979   

TargetAlpha-carbonic anhydrase(Helicobacter pylori (strain G27))
Universit£

LigandPNGBDBM26979(CHEMBL69710 | Cl- | POTASSIUM CHLORIDE | SODIUM CH...)
Affinity DataKi:  2.70E+6nM ΔG°:  -3.44kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition of Vibrio cholerae alpha carbonic anhydrase preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

LigandPNGBDBM26979(CHEMBL69710 | Cl- | POTASSIUM CHLORIDE | SODIUM CH...)
Affinity DataKi:  6.00E+6nM ΔG°:  -2.98kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase(Vibrio cholerae)
Universit£

LigandPNGBDBM26979(CHEMBL69710 | Cl- | POTASSIUM CHLORIDE | SODIUM CH...)
Affinity DataKi:  8.10E+6nM ΔG°:  -2.80kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition of Vibrio cholerae carbonic anhydrase beta preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma carbonic anhydrase family protein(Vibrio cholerae)
Universit£

LigandPNGBDBM26979(CHEMBL69710 | Cl- | POTASSIUM CHLORIDE | SODIUM CH...)
Affinity DataKi:  8.80E+6nM ΔG°:  -2.76kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition of Vibrio cholerae recombinant carbonic anhydrase gamma expressed in Escherichia coli DE3 cells preincubated for 15 mins by stopped-flow C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Vibrio cholerae serotype O1 (strain ATCC 39315 / E...)
Universit£

LigandPNGBDBM26979(CHEMBL69710 | Cl- | POTASSIUM CHLORIDE | SODIUM CH...)
Affinity DataKi:  9.30E+6nM ΔG°:  -2.72kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition of Flaveria bidentis carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

LigandPNGBDBM26979(CHEMBL69710 | Cl- | POTASSIUM CHLORIDE | SODIUM CH...)
Affinity DataKi:  2.00E+8nM ΔG°:  -0.937kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition of Helicobacter pylori alpha carbonic anhydrase preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair