BDBM270138 (2R,3S)-N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-2-pyridinyl)-4H-1,2,4-triazol-3-yl)-3-(5-methoxy-2-pyrazinyl)-2-butanesulfonamide, (2S,3R)-N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-2-pyridinyl)-4H-1,2,4-triazol-3-yl)-3-(5-methoxy-2-pyrazinyl)-2-butanesulfonamide::US10058550, Example 705.0::US10058550, Example 708.0::US10221162, Example 708.0::US9845310, Example 708.0
SMILES COc1cccc(n1)-c1nnc(NS(=O)(=O)[C@H](C)[C@@H](C)c2cnc(OC)cn2)n1-c1c(OC)cccc1OC
InChI Key InChIKey=PDPYRKCYBUPCGL-HZPDHXFCSA-N
Data 6 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 270138
Affinity DataEC50: 0.170nMpH: 7.5Assay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...More data for this Ligand-Target Pair
Affinity DataEC50: 0.180nMpH: 7.5Assay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...More data for this Ligand-Target Pair