BDBM2732 (1R,2R)-N-[cis-2-(6-Fluoro-2-hydroxy-3-propionylphenyl)cyclopropyl]-N-[2-(5-bromopyridyl)]urea::1-(5-bromopyridin-2-yl)-3-[(1R,2R)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea::urea-PETT deriv. 17

SMILES CCC(=O)c1ccc(F)c([C@H]2C[C@H]2NC(=O)Nc2ccc(Br)cn2)c1O

InChI Key InChIKey=VRAJWAGCJIXJHQ-WCQYABFASA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 2732   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Medivir

LigandPNGBDBM2732((1R,2R)-N-[cis-2-(6-Fluoro-2-hydroxy-3-propionylph...)
Affinity DataIC50:  3.80nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Medivir

LigandPNGBDBM2732((1R,2R)-N-[cis-2-(6-Fluoro-2-hydroxy-3-propionylph...)
Affinity DataIC50:  83nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Medivir

LigandPNGBDBM2732((1R,2R)-N-[cis-2-(6-Fluoro-2-hydroxy-3-propionylph...)
Affinity DataIC50:  16nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair