BDBM27342 9-(4-chlorophenyl)-8-(2,4-dichlorophenyl)-6-(4-methylpiperazin-1-yl)-9H-purine::Purine antagonist, 3f

SMILES CN1CCN(CC1)c1ncnc2n(c(nc12)-c1ccc(Cl)cc1Cl)-c1ccc(Cl)cc1

InChI Key InChIKey=QMTPGEKECKOWFW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 27342   

TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM27342(9-(4-chlorophenyl)-8-(2,4-dichlorophenyl)-6-(4-met...)
Affinity DataKi:  5.20nM ΔG°:  -11.5kcal/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM27342(9-(4-chlorophenyl)-8-(2,4-dichlorophenyl)-6-(4-met...)
Affinity DataKi:  5.90nM ΔG°:  -11.4kcal/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed