BDBM27500 5,6-dihydrophenanthridin-6-one::5H-Phenanthridin-6-one::5H-Phenanthridin-6-one (PTD)::6-(5H)-Phenanthridinone::CHEMBL45245::PND::Phenanthridone::phenanthridin-6(5H)-one
SMILES O=c1[nH]c2ccccc2c2ccccc12
InChI Key InChIKey=RZFVLEJOHSLEFR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 27500
Affinity DataIC50: 85nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
Affinity DataIC50: 331nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
Affinity DataIC50: 520nMAssay Description:Inhibition of PARP-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:The compound was tested for poly(ADP-ribose)polymerase (PARP) inhibitionMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 520nMAssay Description:Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibitory activity against Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of calf thymus ARTD1 assessed as incorporation of [Ade-U-14C]-NAD+ after 10 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair