BDBM275886 US10071965, Compound PT420
SMILES CCc1ccn(Cc2ccccc2C#N)c(=O)c1
InChI Key InChIKey=BUXQQYGXJPPCAU-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 275886
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
The Research Foundation For The State University of New York
US Patent
The Research Foundation For The State University of New York
US Patent
Affinity DataKi: 29.6nM ΔG°: -10.3kcal/molepH: 7.5 T: 2°CAssay Description:10 μM saFabI, 15 μM inhibitor, and 500 μM NADPH were preincubated overnight at room temperature followed by a 1:200 dilution into reac...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
The Research Foundation For The State University of New York
US Patent
The Research Foundation For The State University of New York
US Patent
Affinity DataKi: 110nMpH: 7.5Assay Description:Kinetics were performed on a Cary 100 spectrophotometer (Varian) at 20° C. Reaction velocities were measured by monitoring the oxidation of NAD(P)H t...More data for this Ligand-Target Pair