BDBM27718 2-(3-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)propyl)phenanthridin-6(5H)-one::2-[3-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-propyl]-5H-phenanthridin-6-one::2-[3-(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)propyl]-5,6-dihydrophenanthridin-6-one::CHEMBL194482::phenanthridinone analogue, 14
SMILES O=c1[nH]c2ccc(CCCN3CCC(=CC3)c3ccccc3)cc2c2ccccc12
InChI Key InChIKey=ANKUJWLWOYNWFQ-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 27718
Affinity DataIC50: 82nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
Affinity DataIC50: 119nMAssay Description:Inhibition of human recombinant PARP1More data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:In vitro inhibitory concentration against Poly(ADP-ribose) polymerase 1More data for this Ligand-Target Pair
Affinity DataIC50: 84nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair