BDBM285670 US10077273, Compound GD-07

SMILES Cc1n[nH]c2OC(N)=C(C#N)C(C)(c12)c1cccc(c1)[N+]([O-])=O

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 285670   

TargetSerine hydroxymethyltransferase, mitochondrial(Homo sapiens (Human))
The Trustees of Princeton University

US Patent
LigandPNGBDBM285670(US10077273, Compound GD-07)
Affinity DataIC50: >5.00E+3nMpH: 7.4Assay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails US Patent