BDBM292569 (S)-N-(2-(diethylamino)propyl)-2-((2-methoxyethyl)amino) 6 (5 (thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-3-yl)isonicotinamide::US10100058, Example 225
SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(NCCOC)nc(c1)-c1cnn2ccc(nc12)-c1cccs1
InChI Key InChIKey=INEJCFWLGXNWSN-SFHVURJKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 292569
TargetCalcium/calmodulin-dependent protein kinase type II subunit delta(Homo sapiens (Human))
Gilead Sciences
US Patent
Gilead Sciences
US Patent
Affinity DataIC50: 0.0800nMAssay Description:The biochemical activity of recombinant CaMKIIδ was measured by monitoring the phosphorylation of a target peptide using Homogenous Time Resolve...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit delta(Homo sapiens (Human))
Gilead Sciences
US Patent
Gilead Sciences
US Patent
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of recombinant human full length His-tagged CaMK2delta expressed in baculovirus using Biotin labelled STK1 as substrate after 1 hr in pres...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit delta(Homo sapiens (Human))
Gilead Sciences
US Patent
Gilead Sciences
US Patent
Affinity DataEC50: 43.7nMAssay Description:CaMKII activity in neonatal rat ventricular myocytes (NRVM) was measured by monitoring the phosphorylation level of phospholamban using high-content ...More data for this Ligand-Target Pair