BDBM29310 dithioether 1,3,4-thiadiazole, 8c

SMILES COc1ccc(CSc2nnc(SCc3ccc(OC)cc3)s2)cc1

InChI Key InChIKey=UDLMBXIYIDCCSA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29310   

TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Burnham Institute For Medical Research

LigandPNGBDBM29310(dithioether 1,3,4-thiadiazole, 8c)
Affinity DataIC50: >1.00E+5nMAssay Description:Compounds were tested for their ability to inhibit JNK1 phosphorylation of ATF2 in the Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Burnham Institute For Medical Research

LigandPNGBDBM29310(dithioether 1,3,4-thiadiazole, 8c)
Affinity DataAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed