BDBM293872 3-({[(4R)-7-{methyl[4-(2,2,2-trifluoroethoxy)phenyl]amino}-3,4-::US10106534, Example 214

SMILES CN(c1ccc(OCC(F)(F)F)cc1)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1

InChI Key InChIKey=WRNNZQTYKUGDCM-INIZCTEOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 293872   

TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM293872(3-({[(4R)-7-{methyl[4-(2,2,2-trifluoroethoxy)pheny...)
Affinity DataIC50:  550nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent