BDBM295680 US10112931, Example 30
SMILES C[C@H](Nc1nccc(n1)N1[C@@H](COC1=O)[C@H](C)C(F)(F)F)c1nc(no1)-c1ccc(Cl)cc1
InChI Key InChIKey=VWTGBFKWGWEASC-MJVIPROJSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 295680
Affinity DataIC50: 472nMpH: 7.4 T: 2°CAssay Description:Mutant IDH1 R132H catalytic activity was monitored using the quantitative liquid chromatography/mass spectrometry (LC-MS) detection of 2-HG, a produc...More data for this Ligand-Target Pair
Affinity DataIC50: 1.09E+3nMpH: 7.5 T: 2°CAssay Description:The IDH1 (R132H) mutant catalyzes the reduced form of NADP+ (NADPH) and α-ketoglutarate (α-KG) to form nicotinamide adenine dinucleotide ph...More data for this Ligand-Target Pair