BDBM297318 1-Cyclopropyl-1-[3-(dimethyl-1H-1,2,3-triazol-5-yl)-8-fluoro-5-[(S)-(2-fluorophenyl)(oxan-4-yl)methyl]-5H-pyrido[3,2-b]indol-7-yl]ethan-1-ol::US10112941, Example 447::US10112941, Example 448

SMILES Cc1[nH]nn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1F)c1cc(c(F)cc21)C(C)(O)C1CC1

InChI Key InChIKey=XCYSJRXQRQOBEI-CYZZXXEPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 297318   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM297318(1-Cyclopropyl-1-[3-(dimethyl-1H-1,2,3-triazol-5-yl...)
Affinity DataIC50: <5nMAssay Description:All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM297318(1-Cyclopropyl-1-[3-(dimethyl-1H-1,2,3-triazol-5-yl...)
Affinity DataIC50: <5nMAssay Description:All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent