BDBM297397 US10117858, Example 10::US10117858, Example 9::US20240058315, Example 10
SMILES CC(O)(CNC(=O)c1nc(-c2ccc(Cl)cc2Cl)c(cc1N)C(F)(F)F)C(F)(F)F
InChI Key InChIKey=KGUOYCPINMKTEY-UHFFFAOYSA-N
Data 4 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 297397
Affinity DataEC50: 90nMAssay Description:Fischer Rat Thyroid (FRT) epithelial cells, stably expressing human ΔF508-CFTR were used as monolayer cultures on permeable supports. Cl− ...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataEC50: 112nMAssay Description:Fischer Rat Thyroid (FRT) epithelial cells, stably expressing human ΔF508-CFTR were used as monolayer cultures on permeable supports. Cl− ...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataEC50: 90nMAssay Description:Fischer Rat Thyroid (FRT) epithelial cells, stably expressing human ΔF508-CFTR were used as monolayer cultures on permeable supports. Cl− ...More data for this Ligand-Target Pair
Affinity DataEC50: 112nMAssay Description:Fischer Rat Thyroid (FRT) epithelial cells, stably expressing human ΔF508-CFTR were used as monolayer cultures on permeable supports. Cl− ...More data for this Ligand-Target Pair