BDBM304402 (R)-2-fluoro-5-(4-(5-(2-hydroxypropan-2-yl)-4-(trifluoromethyl)pyrimidin-2-yl)-3-isopropylpiperazin-1-yl)-N-methylbenzenesulfonamide::US10144715, Compound 10-3

SMILES CNS(=O)(=O)c1cc(ccc1F)N1CCN([C@@H](C1)C(C)C)c1ncc(c(n1)C(F)(F)F)C(C)(C)O

InChI Key InChIKey=ZFAZSJUOGZNAMM-KRWDZBQOSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 304402   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304402((R)-2-fluoro-5-(4-(5-(2-hydroxypropan-2-yl)-4-(tri...)
Affinity DataKi:  5nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304402((R)-2-fluoro-5-(4-(5-(2-hydroxypropan-2-yl)-4-(tri...)
Affinity DataKi:  135nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent