BDBM304433 (R)-1-(2-((R)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)ethan-1-ol::US10144715, Compound 12-3

SMILES CC(C)[C@@H]1CN(CCN1c1ncc([C@H](C)O)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O

InChI Key InChIKey=RPEJMRBNVYJBHP-GUYCJALGSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 304433   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304433((R)-1-(2-((R)-4-(4-fluoro-3-(methylsulfonyl)phenyl...)
Affinity DataKi:  6nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304433((R)-1-(2-((R)-4-(4-fluoro-3-(methylsulfonyl)phenyl...)
Affinity DataKi:  168nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent