BDBM308060 US10011593, Ex. 11::US9650366, 11
SMILES Nc1ncc(cc1C#Cc1cccc(NC(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)c1)-c1nnn(CCCO)n1
InChI Key InChIKey=AOCNJYRBRZNBTL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 308060
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Allergan
US Patent
Allergan
US Patent
Affinity DataKi: 158nMAssay Description:Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...More data for this Ligand-Target Pair
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Allergan
US Patent
Allergan
US Patent
Affinity DataIC50: 158nMAssay Description:PKR: Commercially available recombinant human GST-PKR (SignalChem, Canada; 1.5 uM-2 uM stock) is diluted to 500 nM in assay buffer (20 mM Tris-HCl, p...More data for this Ligand-Target Pair