BDBM31062 5-methyl-N-(5-quinolinyl)-2-thiophenesulfonamide::5-methyl-N-(5-quinolyl)thiophene-2-sulfonamide::5-methyl-N-quinolin-5-yl-thiophene-2-sulfonamide::5-methyl-N-quinolin-5-ylthiophene-2-sulfonamide::MLS000060442::SMR000067302::cid_2082098

SMILES Cc1ccc(s1)S(=O)(=O)Nc1cccc2ncccc12

InChI Key InChIKey=XSYLVTQRXJCUTP-UHFFFAOYSA-N

Data  7 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 31062   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM31062(5-methyl-N-(5-quinolinyl)-2-thiophenesulfonamide |...)
Affinity DataEC50:  2.76E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM31062(5-methyl-N-(5-quinolinyl)-2-thiophenesulfonamide |...)
Affinity DataEC50: >9.51E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM31062(5-methyl-N-(5-quinolinyl)-2-thiophenesulfonamide |...)
Affinity DataEC50:  9.62E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM31062(5-methyl-N-(5-quinolinyl)-2-thiophenesulfonamide |...)
Affinity DataEC50:  3.91E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay