BDBM31175 thiazol-2-amine, 5

SMILES Nc1nc(cs1)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=HYAHAIVZFRFEBU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 31175   

TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia At Charlottesville

LigandPNGBDBM31175(thiazol-2-amine, 5)
Affinity DataIC50:  3.00E+3nMAssay Description:His6-CBFbeta (1-141) was expressed and purified with the exception of the protease cleavage step. Cerulean-Runt domain fusion protein (Runx1 41-190) ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia At Charlottesville

LigandPNGBDBM31175(thiazol-2-amine, 5)
Affinity DataIC50:  9.00E+3nMpH: 7.5 T: 2°CAssay Description:For the FRET measurements, the Cerulean-Runt (Runx1 41-190) and Venus-CBFbeta (1-141) fusion proteins were dialyzed into FRET assay buffer. Protein c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed