BDBM312151 (E)-6,8-dihydroxy-2-(4-hydroxyphenyl)-4-(prop-1-enyl)isoquinolin-1(2H)-one ::US9604931, 15i::US9623021, Compound 15i
SMILES C\C=C\c1cn(-c2ccc(O)cc2)c(=O)c2c(O)cc(O)cc12
InChI Key InChIKey=QAGWYKCFYYZWRQ-NSCUHMNNSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 312151
Affinity DataKi: 1.66nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair
Affinity DataKi: 1.66nMAssay Description:Recombinant ER-α or ER-β ligand binding domain (LBD) was combined with [3H]E2 (PerkinElmer, Waltham, Mass.) in buffer A (10 mM Tris, pH 7.4...More data for this Ligand-Target Pair
Affinity DataKi: 102nMAssay Description:Recombinant ER-α or ER-β ligand binding domain (LBD) was combined with [3H]E2 (PerkinElmer, Waltham, Mass.) in buffer A (10 mM Tris, pH 7.4...More data for this Ligand-Target Pair
Affinity DataKi: 102nMAssay Description:Estrogen receptor (ERβ) binding affinity of the NRBAs was also determined using an in vitro competitive radioligand-binding assay with [3H]-estr...More data for this Ligand-Target Pair