BDBM312450 2-[6,6-Difluoro-3-(3-methyl-[1,2,4]thiadiazol-5-yl)-4,5,6,7-tetrahydro-benzo[b]thiophen-2-ylcarbamoyl]-cyclopent-1-enecarboxylic acid::US9604977, Example 196

SMILES Cc1nsc(n1)-c1c(NC(=O)C2=C(CCC2)C(O)=O)sc2CC(F)(F)CCc12

InChI Key InChIKey=PMBAFHVXXUHCIN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 312450   

TargetFatty acid-binding protein 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM312450(2-[6,6-Difluoro-3-(3-methyl-[1,2,4]thiadiazol-5-yl...)
Affinity DataIC50:  68nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid-binding protein, adipocyte(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM312450(2-[6,6-Difluoro-3-(3-methyl-[1,2,4]thiadiazol-5-yl...)
Affinity DataIC50:  22nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent