BDBM312839 4-(ethylamino)-1-[3-[2-[(3R)- 3-hydroxy-1-methyl-2-oxo- pyrrolidin-3-yl]ethynyl] phenyl]pyrazolo[4,3-c]pyri- dine-3-carboxamide::US9605005, Example 129

SMILES CCNc1nccc2n(nc(C(N)=O)c12)-c1cccc(c1)C#C[C@]1(O)CCN(C)C1=O

InChI Key InChIKey=KXZGFLMXAWGPHY-QFIPXVFZSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 312839   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM312839(4-(ethylamino)-1-[3-[2-[(3R)- 3-hydroxy-1-methyl-2...)
Affinity DataKi:  0.0500nMAssay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) was monit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent