BDBM315247 (−) 3-{3-[(cyclopentyl{3-fluoro-4-[6-methyl-5-(trifluoromethyl)pyridin-3-yl]phenyl}acetyl)amino]-2-methylphenyl}propanoic acid, Single Enantiomer::US10172814, Example 197

SMILES Cc1c(CCC(O)=O)cccc1NC(=O)C(C1CCCC1)c1ccc(c(F)c1)-c1cnc(F)c(c1)C(F)(F)F

InChI Key InChIKey=IAQRXESEEPXFHB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 315247   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM315247((−) 3-{3-[(cyclopentyl{3-fluoro-4-[6-methyl-...)
Affinity DataIC50:  19.3nMAssay Description:Recombinant proteins (human isoforms) of PTGES containing a FLAG tag, expressed in baculovirus infected insect cells (Hi-5) and purified by affinity ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent