BDBM315605 (3-Chloro-5-methoxy- pyridin-2-yl)-[4-fluoro-3- (7-morpholin-4-yl- quinazolin-4-yl)phenyl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.09 (s, 1H), 8.28 (d, J = 2.6, 1H), 7.62-7.55 (m, 3H), 7 55- 7.49 (m, 2H), 7.41-7.32 (m, 1H), 7.21-7.18 (m, 1H), 6.16 (d, J = 6.1, 1H), 6.03 (d, J = 6.1, 1H), 3.85 (s, 3H), 3.80-3.75 (m, 4H), 3.47-3.42 (m, 4H)::US10172859, Example 31::US11065253, Example 31::US9732094, Example 31
SMILES COc1cnc(C(O)c2ccc(F)c(c2)-c2ncnc3cc(ccc23)N2CCOCC2)c(Cl)c1
InChI Key InChIKey=WUHDWUZGBYYHTQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 315605
Affinity DataIC50: <3nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 μg of DNA-PK/protein complex and 100 n...More data for this Ligand-Target Pair