BDBM31651 tetrahydrobenzothiophene (THBT), 18

SMILES Cc1cccc(C)c1C(=O)C1CCCc2sc(NC(=O)c3ccccc3[N+]([O-])=O)c(C(N)=O)c12

InChI Key InChIKey=UVBIDCXWPPYKMW-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 31651   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gsk

LigandBDBM31651(tetrahydrobenzothiophene (THBT), 18)Copy SMILESCopy InChI

Affinity DataIC50:  5.01E+3nMpH: 7.5 T: 2°CAssay Description:Inhibition of PDE4 is measured using a luminescence-coupled assay system developed by Cambrex. This assay system couples the formation of AMP, derive...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Gsk

LigandBDBM31651(tetrahydrobenzothiophene (THBT), 18)Copy SMILESCopy InChI

Affinity DataIC50:  2.51E+3nMpH: 7.5 T: 2°CAssay Description:Inhibition of PDE4 is measured using a luminescence-coupled assay system developed by Cambrex. This assay system couples the formation of AMP, derive...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI