BDBM31809 Apogossypol derivative, 8k
SMILES CC(NC(=O)c1c(O)c(O)cc2c(O)c(c(C)cc12)-c1c(C)cc2c(C(=O)NC(C)c3ccc(Cl)cc3)c(O)c(O)cc2c1O)c1ccc(Cl)cc1
InChI Key InChIKey=GWXWVWQUYKMTOZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 31809
Affinity DataIC50: 270nM Kd: 110nMpH: 7.4 T: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
Affinity DataIC50: 490nMpH: 7.4 T: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
TargetBcl-2 homologous antagonist/killer(Homo sapiens)
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of Mcl-1/Bak (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 400nMT: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Burnham Institute For Medical Research
Burnham Institute For Medical Research
Affinity DataIC50: 230nMpH: 7.4 T: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair