BDBM320251 3-(5-Ethyl-1,3- thiazol-2-yl)-5- {[(2S)-4- methylmorpholin- 2-yl]methoxy}- N-{(1R)-1-[6- (trifluoromethyl) pyridazin-3- yl]ethyl} benzamide::US10174016, Example 418

SMILES C[C@@H](NC(=O)c1cc(OC[C@@H]2CN(C)CCO2)cc(c1)-c1ncc(CO)s1)c1ccc(nn1)C(F)(F)F

InChI Key InChIKey=LQESXXUCKRJIMX-KDOFPFPSSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 320251   

TargetP2X purinoceptor 2(Homo sapiens (Human))
Beyer Aktiengesellschaft

US Patent
LigandPNGBDBM320251(3-(5-Ethyl-1,3- thiazol-2-yl)-5- {[(2S)-4- methylm...)
Affinity DataIC50:  1.56E+3nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 3(Homo sapiens (Human))
Beyer Aktiengesellschaft

US Patent
LigandPNGBDBM320251(3-(5-Ethyl-1,3- thiazol-2-yl)-5- {[(2S)-4- methylm...)
Affinity DataIC50:  23nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent