BDBM321157 US10174049, Example 24::US9738658, Example 24::US9796729, 24

SMILES CC(C)n1ccc2cc(cc(N3CCOCC3)c12)N1CCOc2ncnc(N)c2C1=O

InChI Key InChIKey=AYFZEMJCCNOWIR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 321157   

TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Glaxosmithkline

US Patent
LigandPNGBDBM321157(US10174049, Example 24 | US9738658, Example 24 | U...)
Affinity DataIC50:  82.2nMAssay Description:For inhibition of triacylglycerol product formation, 11 uL reactions were run in white Polyplate-384 (PerkinElmer6007300) starting with a 30 minute p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Glaxosmithkline

US Patent
LigandPNGBDBM321157(US10174049, Example 24 | US9738658, Example 24 | U...)
Affinity DataIC50:  82.2nMAssay Description:For inhibition of triacylglycerol product formation, 11 uL reactions were run in white Polyplate-384 (PerkinElmer6007300) starting with a 30 minute p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Glaxosmithkline

US Patent
LigandPNGBDBM321157(US10174049, Example 24 | US9738658, Example 24 | U...)
Affinity DataIC50:  82.2nMAssay Description:For inhibition of triacylglycerol product formation, 11 uL reactions were run in white Polyplate-384 (PerkinElmer6007300) starting with a 30 minute p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent