BDBM323034 (1R,2R or 1S,2S)-N-(5-Cyano-1-methyl- 1H-pyrazol-4-yl)-2-[4-(1H-pyrazol-3- yl)benzoyl]cyclohexanecarboxamide::US10183947, Example 18a::US10183947, Example 18b::US10508119, Example 18b

SMILES Cn1ncc(NC(=O)C2CCCCC2C(=O)c2ccc(cc2)-c2cc[nH]n2)c1C#N

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 323034   

TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM323034((1R,2R or 1S,2S)-N-(5-Cyano-1-methyl- 1H-pyrazol-4...)
Affinity DataIC50:  28nMAssay Description:Compounds were tested in a competition binding assay using 3H-MK591 as tracer. (Preparation of MK-591 is described in Bioorg. Med. Chem. Lett. 1999, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM323034((1R,2R or 1S,2S)-N-(5-Cyano-1-methyl- 1H-pyrazol-4...)
Affinity DataIC50:  3.70E+3nMAssay Description:Compounds were tested in a competition binding assay using 3H-MK591 as tracer. (Preparation of MK-591 is described in Bioorg. Med. Chem. Lett. 1999, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent