BDBM325296 US10189841, Compound I-502::US10399980, Compound I-502

SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(CC3CN(C3)c3nccc(n3)C(F)(F)F)c2n1

InChI Key InChIKey=XBVAKLMIEUXVEC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 325296   

TargetUbiquitin carboxyl-terminal hydrolase 1(Homo sapiens (Human))
Forma Therapeutics

US Patent
LigandPNGBDBM325296(US10189841, Compound I-502 | US10399980, Compound ...)
Affinity DataIC50: >2.00E+3nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 1(Homo sapiens (Human))
Forma Therapeutics

US Patent
LigandPNGBDBM325296(US10189841, Compound I-502 | US10399980, Compound ...)
Affinity DataIC50: <0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent