BDBM329530 1-(5-(2-methyl-4- (((1S,2S)-2-(5- methylpyridin-2- yl)cyclopropyl)methoxy) pyrimidin-5-yl)pyridin-2- yl)propan-1-ol::US9663513, 143::US9663513, 144

SMILES CCC(O)c1ccc(cn1)-c1cnc(C)nc1OC[C@H]1C[C@@H]1c1ccc(C)cn1

InChI Key InChIKey=LKJXWEAXNIDLEV-HVHHGIHYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 329530   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329530(1-(5-(2-methyl-4- (((1S,2S)-2-(5- methylpyridin-2-...)
Affinity DataKi:  0.160nMAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329530(1-(5-(2-methyl-4- (((1S,2S)-2-(5- methylpyridin-2-...)
Affinity DataKi:  0.730nMAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent