BDBM331412 8-[(3-Fluoropyridin-2-yl)(oxan-4-yl)methyl]-5,11-bis[4-(2H3)methyl-1-methyl-1H-1,2,3-triazol-5-yl]-3,8,10-triazatricyclo[7.4.0.02,7]trideca-1(13),2(7),3,5,9,11-hexaene::US9725449, Example 247::US9725449, Example 248
SMILES Cc1nnn(C)c1-c1cnc2c(c1)n(C(C1CCOCC1)c1ncccc1F)c1nc(ccc21)-c1c(C)nnn1C
InChI Key InChIKey=CPHYLBGDJHWKNQ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 331412
TargetBromodomain-containing protein 4 [1-477]/[333-460]/[44-168]/[44-460](Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: <10nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [1-477]/[333-460]/[44-168]/[44-460](Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: <1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair