BDBM33238 thieno[2,3-d]pyrimidine, 34e

SMILES CCNC(=O)c1cc2c(nc(N)nc2s1)-c1cc(OCCN(C)C)c(Cl)cc1Cl

InChI Key InChIKey=FFCLCTHAQCJCLU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 33238   

TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM33238(thieno[2,3-d]pyrimidine, 34e)
Affinity DataIC50:  127nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed