BDBM33243 thieno[2,3-d]pyrimidine, 34j

SMILES CCNC(=O)c1cc2c(nc(N)nc2s1)-c1cc(OCCNC2CCCCC2)c(Cl)cc1Cl

InChI Key InChIKey=ZDXVGFKXNJBZGF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 33243   

TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM33243(thieno[2,3-d]pyrimidine, 34j)
Affinity DataIC50:  87nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed