BDBM332677 US10196374, Example 5
SMILES CC(C)[C@H](NC(=O)C(C)(F)F)[C@H](Oc1ccc2n(ncc2c1)-c1ccc(=O)n(C)c1)c1cccc(Cl)c1
InChI Key InChIKey=GKXKDDYZHCNTKR-LOSJGSFVSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 332677
Affinity DataEC50: 2.51nMAssay Description:A reporter cell line (ChagoK1 18:7:2 s4/GRE) was established by stable transfection of the human bronchogenic carcinoma cell line, ChaGo K1 (ATCC: HT...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:A reporter cell line (ChagoK1 18:7:2 s4/GRE) was established by stable transfection of the human bronchogenic carcinoma celline, ChaGo K1 (ATCC: HTB ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Transrepression activity at glucocorticoid receptor (unknown origin) expressed in human ChaGoK1 cells assessed as inhibition of PMA-stimulated gene e...More data for this Ligand-Target Pair
Affinity DataEC50: 2.90nMAssay Description:Transactivation activity at glucocorticoid receptor (unknown origin) expressed in human ChaGoK1 cells incubated for 24 hrs by beta-galactosidase repo...More data for this Ligand-Target Pair
Affinity DataIC50: 324nMAssay Description:Antagonist activity at glucocorticoid receptor (unknown origin) expressed in human ChaGoK1 cells assessed as inhibition of dexamethasone induced tran...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Displacement of fluormone RED from human full length glucocorticoid receptor after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair