BDBM333584 1-(3-tert- butylisoxazol- 5-yl)-3-(3- (6,7- dimethoxy- quinazolin- 4- yloxy)phenyl) urea::US9730937, Example 132
SMILES COc1cc2cccc(Oc3cccc(NC(=O)Nc4cc(no4)C(C)(C)C)c3)c2cc1OC
InChI Key InChIKey=BZVUGCZMOBTQMC-UHFFFAOYSA-N
Data 3 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 333584
Affinity DataKd: <250nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Ambit Biosciences
US Patent
Ambit Biosciences
US Patent
Affinity DataKd: 750nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
Affinity DataKd: 750nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair