BDBM34098 benzamide derivative, 14b

SMILES Fc1ccccc1N1CCN(CC(=O)Nc2cccc(c2)C(F)(F)F)CC1

InChI Key InChIKey=BCIUYVKYSDASDK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 34098   

TargetHexokinase-4(Homo sapiens (Human))
Shanghai Institutes For Biological Sciences

LigandPNGBDBM34098(benzamide derivative, 14b)
Affinity DataAssay Description:The GK activity was assessed spectrometrically by a coupled reaction with glucose-6-phosphate dehydrogenase (G6PDH). Briefly, GK catalyzes glucose ph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
Shanghai Institutes For Biological Sciences

LigandPNGBDBM34098(benzamide derivative, 14b)
Affinity DataIC50:  7.85E+4nMpH: 7.2 T: 2°CAssay Description:The enzymatic inhibition of phosphorylase activity was monitored using microplate reader (Bio-Rad). In brief, GPa activity was measured in the direct...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed