BDBM341808 US10544104, Compound 124::US9765037, Compound 124

SMILES CC(C)COc1ccc2cc(ccc2c1)-c1nn(CC2CCN(C)CC2)c2ncnc(N)c12

InChI Key InChIKey=GOKRPYKIPRDTFC-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 341808   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM341808(US10544104, Compound 124 | US9765037, Compound 124)
Affinity DataIC50:  3.78E+3nMAssay Description:Inhibition of human tyrosine kinases.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University of Washington Through Its Center For

US Patent
LigandPNGBDBM341808(US10544104, Compound 124 | US9765037, Compound 124)
Affinity DataIC50:  7.85E+3nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM341808(US10544104, Compound 124 | US9765037, Compound 124)
Affinity DataIC50:  3.78E+3nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University of Washington Through Its Center For

US Patent
LigandPNGBDBM341808(US10544104, Compound 124 | US9765037, Compound 124)
Affinity DataIC50:  7.85E+3nMAssay Description:Inhibition of human tyrosine kinases.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent