BDBM35023 benzothienopyrimidinone deriv., 14h

SMILES CCc1ccc(cc1)-c1ccc2sc3c(nc(CN(C)C)[nH]c3=O)c2c1

InChI Key InChIKey=JSOJYCSDBKJYSB-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35023   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM35023(benzothienopyrimidinone deriv., 14h)
Affinity DataKi:  5nM ΔG°:  -11.3kcal/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM35023(benzothienopyrimidinone deriv., 14h)
Affinity DataKi:  12nM ΔG°:  -10.8kcal/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed