BDBM353195 3-[4-(4-{2-fluoro-5-[(3-fluorobenzyl)amino]phenyl}-1H-pyrrolo[2,3-b]pyridin-2-yl)piperidin-1-yl]propane-1,2-diol::US9796708, Example 427

SMILES OCC(O)CN1CCC(CC1)c1cc2c(ccnc2[nH]1)-c1cc(NCc2cccc(F)c2)ccc1F

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 353195   

TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM353195(3-[4-(4-{2-fluoro-5-[(3-fluorobenzyl)amino]phenyl}...)
Affinity DataIC50:  9nMAssay Description:CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent