BDBM356999 (5-Amino-1-(3-fluoro-2-methylphenyl)-1H-pyrazol-4-yl)(5-chloroindolin-1-yl)methanone::US10214509, Example 57

SMILES Cc1c(F)cccc1-n1ncc(C(=O)N2CCc3cc(Cl)ccc23)c1N

InChI Key InChIKey=SBYWYJFOTFVRCK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 356999   

TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Almirall

US Patent
LigandPNGBDBM356999((5-Amino-1-(3-fluoro-2-methylphenyl)-1H-pyrazol-4-...)
Affinity DataIC50: >3.30E+4nMAssay Description:Cell LinesStable cell lines expressing the full-length protein of the voltage-gated sodium channels Nav1.7 or Nav1.5, with or without one beta-1, bet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Almirall

US Patent
LigandPNGBDBM356999((5-Amino-1-(3-fluoro-2-methylphenyl)-1H-pyrazol-4-...)
Affinity DataIC50:  800nMAssay Description:Cell LinesStable cell lines expressing the full-length protein of the voltage-gated sodium channels Nav1.7 or Nav1.5, with or without one beta-1, bet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent