BDBM357274 2-(((1s,4s)-4-((4-(5- fluoropyridin-3-yl)-5- (methylthio)-3-phenyl-1H- pyrazol-1- yl)methyl)cyclohexyl) methoxy)acetic acid::US10214518, Compound 135

SMILES CSc1c(c(nn1C[C@@H]1CC[C@H](COCC(O)=O)CC1)-c1ccccc1)-c1cncc(F)c1

InChI Key InChIKey=KAHKWAPEWNQHDG-HDICACEKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 357274   

TargetMajor prion protein(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM357274(2-(((1s,4s)-4-((4-(5- fluoropyridin-3-yl)-5- (meth...)
Affinity DataIC50:  220nMAssay Description:Blood collected from healthy human volunteers in aqueous trisodium citrate solution was centrifuged at 150 g for 15 min and the upper layer was recov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent