BDBM35856 acrylic acid derivative, 13

SMILES OC(=O)\C=C\c1ccc(CN2CCCC2=O)cc1OCCc1ccc2ccccc2c1

InChI Key InChIKey=UZFYCISOWWEDLU-VAWYXSNFSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 35856   

TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Ono Pharmaceutical

LigandPNGBDBM35856(acrylic acid derivative, 13)
Affinity DataKi:  110nM EC50:  580nMAssay Description:Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Mus musculus (Mouse))
Ono Pharmaceutical

LigandPNGBDBM35856(acrylic acid derivative, 13)
Affinity DataKi:  2.30E+3nMAssay Description:Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Ono Pharmaceutical

LigandPNGBDBM35856(acrylic acid derivative, 13)
Affinity DataKi:  5.90E+3nM ΔG°:  -7.13kcal/molepH: 6.0 T: 2°CAssay Description:Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Mus musculus (Mouse))
Ono Pharmaceutical

LigandPNGBDBM35856(acrylic acid derivative, 13)
Affinity DataKi:  6.40E+3nM ΔG°:  -7.08kcal/molepH: 6.0 T: 2°CAssay Description:Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed